Interplay of Age and Sex With Clinic and Ambulatory Blood Pressure and Mortality - PubMed
9 hours ago
- #blood pressure
- #cardiovascular disease
- #aging
- Study explores the relationship between clinic and 24-hour ambulatory blood pressure (ABPM) with cardiovascular death (CVD), focusing on age and sex differences.
- Data from 59,124 patients in the Spanish ABPM Registry were analyzed over a median follow-up of 9.7 years, with 2,361 CVD cases.
- Nonlinear relationships between blood pressure parameters (SBP, DBP, PP) and CVD were observed, with significant differences by age and sex.
- Males had higher SBP than females until around 75 years, after which differences diminished.
- High SBP and PP were associated with CVD risk consistently across sexes and ages, with a steeper increase in risk for older females.
- Nighttime BP and 24-hour ABPM were more closely associated with CVD risk in younger individuals compared to office BP.
- The study suggests that guidelines should emphasize 24-hour ABPM for better risk prediction, especially in elderly females.