The Protective Effect of Vitamin C Targeting Oxidative Stress on Renal Function in Patients with Septic Acute Kidney Injury: A Prospective, Randomized Controlled, Pilot Study - PubMed
3 hours ago
- #acute kidney injury
- #vitamin C
- #sepsis
- Study explores vitamin C's effect on reducing acute kidney injury (AKI) in sepsis patients.
- Randomized controlled trial with 40 sepsis patients: 20 received vitamin C (1.5g every 6h for 3 days), 20 received placebo.
- Vitamin C group showed lower AKI incidence (25% vs. 70%) and less need for renal replacement therapy (RRT).
- Vitamin C group had shorter ICU stays (11.8 vs. 13.9 days) and less vasoactive drug use (35% vs. 75%).
- No significant difference in ICU mortality between groups (10% vs. 15%).
- Larger sample size needed to confirm findings.