CU104, a novel barrier function enhancer, improves colitis via modulation of barrier function and immune cell recruitment - PubMed
3 hours ago
- #Barrier Function
- #Inflammatory Bowel Disease
- #Actin Dynamics
- CU104 shows therapeutic potential in colitis models by improving barrier functions and reducing immune cell recruitment.
- It suppresses innate immune responses and inhibits key inflammatory signaling pathways such as NF-κB and IRF.
- CU104 modulates actin dynamics via the ERM pathway, enhancing both intestinal and vascular barrier integrity.