The Great Unbalding
7 days ago
- #hair-loss
- #PP405
- #medical-research
- The Tressless sub-Reddit is a major online community for individuals dealing with hair loss, discussing treatments and sharing experiences.
- Current FDA-approved hair loss treatments like minoxidil (Rogaine) and finasteride (Propecia) have limitations, including side effects and inconsistent results.
- PP405, a new drug developed by Pelage Pharmaceuticals, aims to reactivate dormant hair follicles by reprogramming stem cell metabolism, showing promising early trial results.
- PP405's Phase 2a trial demonstrated significant hair regrowth in some participants within weeks, a notable improvement over existing treatments.
- Despite enthusiasm, experts caution that PP405 is still in early stages, with long-term efficacy and safety yet to be fully established.
- Some individuals, like 'Bob,' have taken experimental approaches, sourcing unverified compounds online in hopes of replicating PP405's effects.
- Pelage Pharmaceuticals is exploring broader applications of stem cell reactivation beyond hair loss, hinting at potential future treatments for aging tissues.
- Funding challenges and regulatory hurdles, such as federal grant suspensions and proposed bans on animal research, could impact PP405's development timeline.