Post-acute coronary syndrome cardiovascular rehabilitation: insights into endpoints, biomarkers and clinical practice - PubMed
5 hours ago
- #secondary prevention
- #acute coronary syndrome
- #cardiac rehabilitation
- Cardiac rehabilitation (CR) is a key multidisciplinary intervention for secondary prevention after acute coronary syndromes (ACS).
- CR reduces mortality, recurrent events, and hospitalizations while improving quality of life and functional capacity.
- Benefits include mitigation of systemic inflammation, attenuation of adverse cardiac remodelling, and promotion of long-term behavioural change.
- Recent advances include digital health tools, telemedicine, and hybrid delivery models to improve accessibility and adherence.
- Pharmacological innovations like PCSK9 inhibitors and inclisiran contribute to residual risk reduction when integrated into CR.
- Mind-body interventions such as yoga and tai chi offer additional physiological and psychological benefits.
- Advanced functional assessments like cardiopulmonary exercise testing enable personalised risk stratification and training prescription.
- Access to CR remains limited, with significant regional variability in implementation and participation.
- Addressing gaps requires harmonised referral systems, multidisciplinary coordination, and patient-centred strategies.
- Ongoing research should focus on integrating emerging therapies and technologies to enhance personalisation and equity.