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New 2030 Global Targets for Histoplasmosis from International Society for Human and Animal Mycology (ISHAM) 2025 Histoplasmosis Working Group - PubMed

4 hours ago
  • #Histoplasmosis
  • #Fungal Infection
  • #Global Health
  • Histoplasmosis is a neglected but deadly fungal infection, especially affecting immunocompromised individuals and those with HIV/AIDS in endemic regions.
  • The disease is underdiagnosed and lacks inclusion in national surveillance systems, leading to delayed treatment and high mortality rates.
  • The International Society for Human and Animal Mycology (ISHAM) formed a Histoplasmosis Working Group in 2025 to address the issue globally.
  • Key challenges include diagnostic delays, underutilization of antigen testing, and limited access to essential treatments like liposomal amphotericin B and itraconazole.
  • Innovations such as lateral flow assays and molecular tools were highlighted as potential solutions.
  • The group proposed a 90-90-90 target by 2030 to improve diagnosis, treatment, and survival rates for histoplasmosis.