Patient Characteristics and Clinical Outcomes in a Specialist Hypertension Clinic: A Pragmatic Real-World Single-Center Observational Study - PubMed
10 hours ago
- #medication adherence
- #real-world outcomes
- #hypertension management
- A retrospective study of 199 patients at a specialist hypertension clinic found significant blood pressure reductions with an average decrease of -13.6/-8.8 mmHg over a median follow-up of 13.8 months.
- Patients were complex, with 32.7% having secondary hypertension and 17.2% resistant hypertension; BP improvements were consistent across clinical subgroups, including those with diabetes, CKD, and obesity.
- Medication non-adherence identified via qualitative urine screening in some patients, and targeted interventions led to subsequent BP improvements, highlighting the clinical value of objective adherence assessment.
- Cardiovascular events were infrequent at 6.5%, but residual cardiovascular risk persisted, indicating that BP control remains challenging despite specialist care.
- The study advocates for larger multicenter studies with longer follow-up to better define predictors of cardiovascular outcomes and optimize care pathways in hypertension management.