Drug-Induced acute Pancreatitis: A Real-World Pharmacovigilance Study Using the Tunisian Databases - PubMed
2 hours ago
- #Acute pancreatitis
- #Drug-induced pancreatitis
- #Pharmacovigilance
- Drug-induced acute pancreatitis (AP) is a rare but recognized cause of AP.
- Study analyzed 13 cases of drug-induced AP out of 1580 AP patients over five years.
- Mean age of affected patients was 55.62 years, with 77% being male.
- Common symptoms: sudden epigastric pain (100%) and elevated lipase (92.3%).
- Implicated drugs: captopril (38.5%), atorvastatin (23.1%), azathioprine (23.1%), metformin, and olanzapine (7.7% each).
- Management involved pain control and proton pump inhibitors, with 84% favorable outcomes.
- Early recognition and reporting are crucial for pharmacovigilance.