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COPT4 interacts with COPT1 or COPT3 to manipulate the signaling response for copper-triggered immunity in Arabidopsis - PubMed

8 hours ago
  • #COPT transporters
  • #copper-triggered immunity
  • #Arabidopsis
  • COPT4 interacts with COPT1 or COPT3 to manipulate copper-triggered immunity (CuTI) in Arabidopsis.
  • Among COPT1 to COPT6, only COPT4 mutation attenuates Cu+-mediated immune responses, despite COPT4 not transporting Cu+ alone.
  • COPT4 forms heterodimers with COPT1 and COPT3, which are crucial for CuTI.
  • The Arabidopsis homolog of anti-oxidant 1 (ATX1) interacts with COPT1 and COPT3 but not COPT4, playing a role in CuTI.
  • The bHLH107-ACS8 module is activated inside plant cells as part of the Cu+-responsive signaling pathway.