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Multidisciplinary international expert consensus recommendations on tissue acquisition in non-small cell lung cancer - PubMed

3 hours ago
  • #NSCLC
  • #Precision Medicine
  • #Biopsy Techniques
  • Precision medicine has improved outcomes for advanced non-small cell lung cancer (NSCLC) and is now being applied to early-stage NSCLC.
  • There is significant variation in diagnostic yields and procedural complications, highlighting the need for a multidisciplinary consensus approach.
  • An international expert panel from the US, Europe, and Asia-Pacific developed consensus recommendations through structured discussions and reviews.
  • Biopsy should target the most advanced stage site, with technique choice depending on the tissue location (e.g., pulmonary nodules, lymph nodes, pleural disease).
  • Optimal biopsy techniques should support diagnosis and staging, considering clinical presentation, diagnostic yield, sample type, invasiveness, and patient-centered care.
  • Funding for the consensus was provided by AstraZeneca, and several authors disclosed conflicts of interest related to pharmaceutical companies.