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Ready or Not, Here They Come: A Practical Guide to Adoptive T cell Therapies for Solid Tumors for Medical Oncologists - PubMed

3 hours ago
  • #Toxicity management
  • #Solid tumors
  • #Adoptive cell therapy
  • Adoptive cell therapies (ACTs) include CARs, BiTES, TILs, and TCR gene modified T cells.
  • ACTs have improved outcomes in hematologic malignancies and show promise in solid tumors.
  • Medical oncologists need to manage unique toxicities like CRS and ICANS.
  • The review provides clinical data on ACTs in solid tumors and toxicity management.
  • Early recognition and evidence-based management of CRS and ICANS are crucial for patient outcomes.