Flare of clonal hematopoiesis, TP53 expansion and prior melphalan drive post-CAR-T myeloid disorders in multiple myeloma - PubMed
3 hours ago
- #multiple myeloma
- #CAR-T therapy
- #myeloid disorders
- Study focuses on post-CAR-T myeloid disorders in multiple myeloma patients.
- Key factors identified: flare of clonal hematopoiesis, TP53 expansion, and prior melphalan treatment.
- Multiple authors report competing interests with pharmaceutical companies like Johnson & Johnson, BMS, and others.
- Research supported by grants from Deutsche José Carreras Leukämie-Stiftung and Deutsche Forschungsgemeinschaft.