Specific gut microbes are associated with the incidence of cardiometabolic disease in the HELIUS cohort - PubMed
4 days ago
- #cardiometabolic disease
- #gut microbiota
- #HELIUS cohort
- Specific gut microbes are linked to cardiometabolic diseases in the HELIUS cohort.
- Higher abundance of Eubacterium xylanophilum group spp. and Akkermansia muciniphila is associated with lower risk of major adverse cardiovascular events (MACE+).
- Ruminococcus gnavus group spp. is associated with higher MACE risk.
- The study involved 4792 participants with fecal samples analyzed using 16S rRNA sequencing.
- Exploratory metabolomics linked Ruminococcus gnavus group spp. to bile acid and acylcarnitine metabolites.
- The findings suggest a longitudinal association between gut microbiota composition and cardiometabolic disease.