Association of Life's Simple 7 with metabolic-associated steatotic liver disease and non-invasive fibrosis markers - PubMed
3 hours ago
- #Liver Fibrosis
- #Life's Simple 7
- #MASLD
- Metabolic-associated steatotic liver disease (MASLD) affects about a third of the global population.
- Life's Simple 7 (LS7), a cardiovascular health metric, was studied for its association with MASLD and liver fibrosis.
- The study included 3204 participants from the Salzburg Colon Cancer Prevention Initiative (Sakkopi).
- LS7 scores were categorized as poor (0-4), intermediate (5-9), and ideal (10-14).
- MASLD prevalence was highest in the poor LS7 group (82%) compared to intermediate (47%) and ideal (16%) groups.
- Higher LS7 scores were significantly associated with lower MASLD risk (RR 0.80; 95% CI 0.79-0.82; p<0.001).
- Associations with liver fibrosis markers were weaker and varied by marker.
- The study highlights the link between cardiometabolic health and liver disease.
- Future research should explore longitudinal changes in LS7 and liver health outcomes.