Progress and Challenges in CAR-T Cell Therapy for Bladder Cancer - PubMed
3 hours ago
- #CAR-T
- #Immunotherapy
- #Bladder Cancer
- Bladder cancer (BC) is a prevalent malignancy with rising global incidence.
- CAR-T cell therapy shows promise in treating BC, especially in advanced stages.
- Key challenges include target selection, the immunosuppressive tumor microenvironment, and lack of clinical validation.
- Preclinical studies and early-phase clinical trials indicate potential antitumor activity of CAR-T in BC.
- Combination strategies and mechanisms of action are under exploration to enhance therapy efficacy.