Spinal and supra-spinal modulation of propofol injection pain by rubbing and distraction: a randomized, partially-blind controlled study - PubMed
4 hours ago
- #pain management
- #anesthesia
- #propofol
- Propofol injection pain (PIP) is common with its standard formulation, but pain can be modulated at spinal or supra-spinal levels.
- A randomized study compared rubbing and distraction (RD) with lidocaine (L) and saline (S) groups in 135 patients.
- PIP incidence and severity (measured by a 0-3 VRS) were significantly lower in L and RD groups compared to S (P<0.001).
- Pain recall one hour after surgery was significantly lower in the RD group than in the S group (P=0.003).
- Rubbing and distraction were as effective as IV lidocaine in reducing PIP, with less postoperative pain recall.