Medication use during pregnancy in Japan from 2005 to 2019: Trends and safety considerations - PubMed
4 days ago
- #medication-safety
- #pregnancy
- #Japan
- Study evaluates medication use during pregnancy in Japan from 2005 to 2019 using the JMDC claims database.
- Acetaminophen was the most commonly dispensed medication during pregnancy across all trimesters.
- Other frequently dispensed medications included analgesics, antiasthmatics, antibiotics, antiemetics, and thyroid medications.
- Annual trends showed increased use of analgesics (mainly acetaminophen), antiasthmatics, antiemetics, and thyroid medications.
- Over 60% of the top 30 most commonly dispensed medications in the first trimester lacked sufficient teratogenic safety evidence.
- The study highlights the urgent need for targeted safety evaluations of medications used during pregnancy in Japan.