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Unraveling the Dynamic Trajectories and Predictive Determinants of Fear of Cancer Recurrence in Breast Cancer Survivors: A Prospective Cohort Study - PubMed

2 days ago
  • #breast cancer
  • #machine learning
  • #fear of recurrence
  • The study explores fear of cancer recurrence (FCR) trajectories in breast cancer survivors.
  • Three distinct FCR trajectories identified: persistently low (47.85%), increasing (32.28%), and decreasing (19.87%).
  • Random Forest (RF) model showed the highest predictive accuracy with ROC AUC of 0.901 and PR AUC of 0.854.
  • Key predictors include demographic, socioeconomic, clinical, and psychosocial factors.
  • The study highlights the importance of early identification of high-risk factors for improving patient outcomes.
  • Limitations include measuring FCR at only six time points and the need for longer-term studies.
  • Future research should focus on evidence-based interventions for managing FCR.