Scientists just found a protein that reverses brain aging
a day ago
- #cognitive decline
- #FTL1 protein
- #brain aging
- Scientists at UCSF discovered a protein called FTL1 that plays a key role in brain aging.
- Excess FTL1 in mice led to memory loss, weaker brain connections, and sluggish cells, mimicking aging effects.
- Blocking FTL1 in old mice reversed cognitive decline, restoring youthful brain function and memory.
- FTL1 affects the hippocampus, the brain region responsible for learning and memory.
- Increasing FTL1 in young mice caused their brains to resemble those of old mice.
- Reducing FTL1 in old mice improved brain cell connections and memory performance.
- FTL1 slows down metabolism in hippocampal cells, but stimulating metabolism can counteract its effects.
- The research suggests potential therapies targeting FTL1 to reverse cognitive decline in aging brains.
- The study was published in Nature Aging and funded by multiple foundations and institutes.