A meta-umbrella review of risk factors for vulvodynia: evidence from demographic, psychosocial, and biomedical domains - PubMed
3 hours ago
- #chronic pain
- #vulvodynia
- #risk factors
- Vulvodynia is a chronic vulvar pain condition with a multifactorial etiology.
- This meta-umbrella review synthesizes evidence on demographic, psychosocial, and biomedical risk factors associated with vulvodynia.
- Strong associations were found with fibromyalgia, recurrent urinary tract infections, recurrent vulvovaginal candidiasis, irritable bowel syndrome, anxiety, depression, systemic inflammation, and allergy/atopy.
- Suggestive evidence was found for interstitial cystitis, endometriosis, and younger age.
- The study analyzed 15 meta-analyses, 28 systematic reviews, and 129 primary studies, involving 30,095 vulvodynia cases and 14,928,868 controls.
- Findings highlight the multifactorial nature of vulvodynia and are crucial for clinical history and future research.