The rate and risk factors for malignancy in patients with inflammatory bowel disease in Crete: a case control study - PubMed
3 hours ago
- #malignancy
- #IBD
- #Crete
- About 30% of IBD patients develop malignancies, the second leading cause of death after cardiovascular diseases.
- Study in Crete found a 4.5% malignancy rate among 2,382 IBD patients, with 11.2% having colorectal cancer.
- Inflammatory CD phenotype was protective against malignancy, while colonic location was a significant risk factor.
- No negative impact on survival or recurrence was observed with biologics or immunomodulators post-cancer diagnosis.
- Majority of malignancies were extraintestinal, with 17.8% mortality rate due to cancer among affected patients.