β-Nicotinamide mononucleotide preserves muscle strength in septic male mice - PubMed
5 days ago
- #β-NMN
- #sepsis
- #muscle-weakness
- Sepsis leads to long-term muscle weakness (ICU-AW) despite recovery of muscle mass.
- Mitochondrial dysfunction and downregulation of Sirt3 are key factors in sepsis-induced muscle weakness.
- β-Nicotinamide mononucleotide (β-NMN) supplementation preserves muscle strength and mitochondrial function in septic mice.
- β-NMN shows potential as a therapeutic strategy for ICU-AW by targeting NAD+ pathways.