Timing and efficacy of doxycycline in macrolide-resistant Mycoplasma pneumoniae pneumonia in children: a single-center retrospective study - PubMed
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- #pediatrics
- #antibiotics
- Study assesses efficacy of doxycycline in treating macrolide-resistant Mycoplasma pneumoniae pneumonia (MRMPP) in children.
- Retrospective analysis of 312 children divided into three groups: AZI (azithromycin only), DOX (doxycycline only), and ATD (azithromycin followed by doxycycline).
- DOX group showed the highest 48-hour fever reduction rate (80%).
- AZI group had higher use of oxygen therapy (77%) and electronic bronchoscopy (75%).
- ATD group had higher use of hormones (39%).
- Early doxycycline use reduces reliance on adjuvant therapies, easing healthcare burden.