Management of classic lichen planopilaris: The EADV task force on hair diseases position statement - PubMed
3 hours ago
- #cicatricial alopecia
- #lichen planopilaris
- #hair diseases
- Lichen planopilaris (LPP) is a primary lymphocytic cicatricial alopecia affecting the vertex or parietal scalp.
- LPP involves CD8+ cytotoxic T cells targeting follicular antigens, leading to inflammation and permanent hair follicle damage.
- Early diagnosis and prompt intervention are crucial to minimize hair loss and prevent disease progression.
- Management of LPP is challenging due to the lack of curative treatments and unpredictable disease and treatment responses.
- First-line treatments include potent topical and intralesional steroids, used alone or in combination with other therapies.
- For moderate to severe LPP, systemic therapy or a combination approach should be considered, tailored to patient needs.
- No head-to-head treatment comparisons exist, and recommendations should be personalized for each patient.