Dermcidin has antiviral activity and protects against influenza - PubMed
7 hours ago
- #dermcidin
- #antiviral activity
- #influenza
- Dermcidin, an antimicrobial peptide, exhibits antiviral activity against influenza viruses by binding to hemagglutinin.
- It extends its antiviral effect to other respiratory viruses such as measles and human coronavirus OC43, beyond influenza.
- Present in all anatomical entry routes for respiratory viruses, dermcidin levels increase during infections and protect mice from influenza.
- Higher levels of dermcidin in asymptomatic individuals compared to symptomatic ones suggest a role in preventing disease symptoms.
- The findings indicate dermcidin's potential as a human-derived product for preventing and treating respiratory viral infections.