Evaluating Infections in Solid Organ Donors Before Transplantation: A Systematic Review of Clinical Practice Guidelines - PubMed
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- #donor-derived infection
- #solid organ transplantation
- #clinical practice guidelines
- Donor-derived infection is a significant risk in solid organ transplantation.
- Clinical practice guidelines for donor evaluation vary across centers and regions.
- The study reviewed 19 clinical practice guidelines and 19 consensus statements.
- Guidelines focused on scope and purpose but lacked emphasis on applicability and development rigor.
- Consistent recommendations exist for hepatitis B, hepatitis C, HIV, Mycobacterium tuberculosis, Toxoplasma gondii, and Treponema pallidum infections.
- Variations in recommendations occur for emerging infections or when screening test performance is poor.
- Most recommendations were ungraded.
- Transparency in evidence synthesis and real-world evaluation of guideline implementation is needed.