'What' and 'How' to Measure in Allergy and Clinical Immunology: A Systematic Review of Core Outcome Sets and Outcome Harmonisation Processes - PubMed
2 hours ago
- #systematic review
- #allergy
- #core outcome sets
- Systematic review aims to map Core Outcome Sets (COS) and other harmonisation processes in allergy and clinical immunology.
- Identifies 22 initiatives from 44 studies, with asthma being the most common focus, and notable gaps in areas like drug allergy.
- Key outcomes frequently included across COS are quality of life, signs and symptoms, exacerbations, and disease control.
- Methodological approaches vary widely; adherence to COS-STAD criteria is inconsistent, affecting transparency and rigor.
- Concludes that strengthening methodology and expanding COS to neglected areas are crucial for improving outcome comparability.