Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review - PubMed
4 hours ago
- #gut microbiota
- #health benefits
- #probiotics
- Probiotics are live microorganisms known to positively impact gut microbiota, linked to various health benefits.
- They are used to treat or prevent conditions like infant colic, cardiovascular disease, respiratory infections, and some cancers.
- Consumer demand for probiotic-enriched foods has grown due to health claims, aiding disorders such as irritable bowel syndrome and allergies.
- Recent microbiome research is advancing probiotic science, including studies on novel strains and their mechanisms.
- Key gaps exist in strain-specific mechanisms, dosages, long-term safety, and interactions with host genetics and diet.
- This review integrates historical aspects, mechanisms, applications, and risks, highlighting next-generation probiotics and genetically engineered microbes.
- It explores synergies with dietary bioactives like polyphenols and fibers for functional foods and targeted therapies.