Eosinophilic oesophagitis: pathophysiology, diagnosis, and treatment - PubMed
a day ago
- #Eosinophilic oesophagitis
- #Gastroenterology
- #Immune-mediated disease
- Eosinophilic oesophagitis is a chronic, immune-mediated condition with eosinophil infiltration in the oesophageal mucosa.
- The disease involves genetic susceptibility, environmental exposures, and immune responses driven by type 2 helper T cells.
- Diagnosis traditionally relies on endoscopic biopsy, but new minimally invasive tests like the oesophageal string test are emerging.
- Treatment options include dietary elimination, drug treatments (e.g., proton pump inhibitors, topical corticosteroids), biologics like dupilumab, and endoscopic dilation.
- Recent advances in targeted treatments and diagnostics are improving long-term care for this increasingly prevalent condition.