TEAD4 Identified as a Potential Biomarker for Gastric Cancer Via Genes Associated with Liquid-Liquid Phase Separation - PubMed
3 hours ago
- #Biomarker
- #TEAD4
- #Gastric Cancer
- TEAD4 identified as a potential biomarker for gastric cancer (GC) via genes linked to liquid-liquid phase separation (LLPS).
- TEAD4 is abnormally overexpressed in GC at mRNA and protein levels, correlating with tumor stage and poorer survival.
- High TEAD4 expression shows strong diagnostic accuracy (AUC > 0.9) and is linked to immune regulation and tumor heterogeneity.
- TEAD4 knockdown in vitro reduces GC cell proliferation, migration, and invasion.
- TEAD4 may serve as a diagnostic, prognostic biomarker and offer insights for therapeutic strategies in GC.