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First evidence of microplastic pollution in human trabecular meshwork and its association with intraocular pressure in glaucoma - PubMed

3 hours ago
  • #microplastics
  • #glaucoma
  • #environmental-pollution
  • First evidence of microplastic pollution found in human trabecular meshwork (TM).
  • Study links microplastic (MP) accumulation in TM to elevated intraocular pressure (IOP) in primary open-angle glaucoma (POAG).
  • Predominant polymers detected: polyamide 66 (PA66), polyvinyl chloride (PVC), and polypropylene (PP).
  • 76.9% of detected MP particles were under 50 μm, relevant to TM pore size.
  • Strong correlation found between total MP burden and maximum recorded IOP (ρ = 0.735, P < 0.001) and preoperative IOP (ρ = 0.797, P < 0.001).
  • Suggests a new etiological pathway for glaucoma related to environmental MP exposure.