Global, regional, and national burden of breast cancer among females, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023 - PubMed

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Breast cancer is a leading cause of mortality and morbidity among females worldwide.
In 2023, there were an estimated 2.30 million breast cancer incident cases, 764,000 deaths, and 24.1 million DALYs globally.
Low-income countries had the highest age-standardized mortality rate (ASMR) despite a low age-standardized incidence rate (ASIR).
High-income countries had the highest ASIR but the lowest ASMR, reflecting better screening and treatment.
Between 1990 and 2023, ASIR increased by 147.2% in low-income countries but only 1.2% in high-income countries.
ASMR decreased by 29.9% in high-income countries but increased by 99.3% in low-income countries.
Risk factors like dietary risks, tobacco use, and high fasting plasma glucose contributed to 28.3% of breast cancer DALYs in 2023.
By 2050, global breast cancer cases are forecasted to reach 3.56 million, with 1.37 million deaths.
The study highlights disparities in breast cancer outcomes, with low-income regions facing rising mortality due to health system deficits.

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