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2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Antiviral Treatment for Mild to Moderate COVID-19 in Adults - PubMed

10 hours ago
  • #COVID-19
  • #clinical guideline
  • #antiviral treatment
  • The Infectious Diseases Society of America released a 2025 clinical practice guideline update on antiviral treatment for adults with mild to moderate COVID-19.
  • The update includes 9 revised recommendations focusing on the use of nirmatrelvir/ritonavir, remdesivir, and molnupiravir.
  • Recommendations are based on a systematic literature review and adhere to the GRADE methodology for evidence certainty and recommendation strength.
  • The guideline provides an algorithm to assist in selecting appropriate antiviral treatments.
  • Potential conflicts of interest among panelists are disclosed, with management strategies in place to mitigate bias.