Reconstitution of sex determination and the testicular niche using mouse pluripotent stem cells - PubMed
3 hours ago
- #testicular niche
- #stem cells
- #sex determination
- Reconstitution of testicular somatic cells from mouse pluripotent stem cells.
- Recapitulation of the sex-determination process in vitro.
- Formation of seminiferous tubules and interstitial tissues.
- Integration of pluripotent stem cell-derived primordial germ cells.
- Support for differentiation into spermatogonial stem cells and functional spermatozoa.
- Potential for creating an alternative source for the male germ line in culture.