Bone marrow-derived mesenchymal stem cells combined with intramuscular injection promote the healing of diabetic foot ulcers: a systematic review and meta-analysis - PubMed
4 hours ago
- #diabetic foot ulcer
- #meta-analysis
- #mesenchymal stem cell
- Systematic review and meta-analysis demonstrates bone marrow-derived mesenchymal stem cell (BMMSC) therapy improves diabetic foot ulcer healing and reduces amputation rates.
- Autologous BMMSCs, combined with intramuscular injection at medium-to-high doses, show optimal efficacy in enhancing healing rates and limb perfusion.
- Patients with shorter diabetes duration, larger ulcer areas, or prolonged non-healing ulcers benefit most significantly from the therapy.