Bile acids are associated with baseline and longitudinal amyloid and tau pathology in patients with Alzheimer's disease - PubMed
5 hours ago
- #Alzheimer's disease
- #Bile acids
- #Neurodegeneration
- Bile acids (BAs) are linked to Alzheimer's disease (AD) pathology, including amyloid-β and tau.
- Lithocholic acid (LCA) and deoxycholic acid (DCA) families are associated with AD biomarkers.
- Longitudinal changes in BA levels correlate with amyloid and tau pathology progression.
- BAs may serve as molecular bridges connecting aging with AD pathology.
- Potential for BAs to be used in developing new biomarkers and therapeutic interventions for AD.