A Link Between Allergy and Hematological Malignancies? Focus on Possible Mechanisms and the Potential Role of Biological Therapies - PubMed
12 hours ago
- #immune dysregulation
- #allergy
- #hematological malignancies
- Immune dysregulation is a common underlying condition for hematological malignancies and allergic disorders.
- The cellular and molecular mechanisms of allergic inflammation may influence carcinogenesis in both solid tumors and hematological malignancies.
- Th2 responses, inflammatory cells, cytokines, and alarmins are key immune pathways studied in the link between allergy and hematological malignancies.
- Biologics' association with the risk of neoplastic diseases, particularly hematological malignancies, is under review.
- Understanding shared immune dysregulation pathways could lead to new preventive or therapeutic approaches for hematological malignancies.
- Future research aims to explore the dual roles of Th2 inflammation mediators in tumor growth stimulation or inhibition.
- Immunotherapy and monoclonal antibody therapies are becoming increasingly important in targeted cancer treatments.