Antioxidant vitamin index and risk of age-related macular degeneration: multicenter validation and clinical translation - PubMed
a day ago
- #Antioxidant Vitamin Index
- #Age-related macular degeneration
- #Nutritional prevention
- The Antioxidant Vitamin Index (AVI) integrates vitamins A, C, and E to measure systemic antioxidant nutritional status.
- Higher AVI is consistently associated with a lower risk of age-related macular degeneration (AMD) across multiple cohorts.
- Dose-response analyses show a progressive decline in AMD risk with increasing AVI levels.
- Machine learning identifies age and AVI as dominant predictors of AMD.
- AVI improves model performance when added to conventional risk factors for AMD.
- The study supports AVI as a potential tool for early screening and nutrition-based prevention of AMD.