Impact and efficacy of systemic antibiotics for peri-implant diseases treatment: A systematic review and meta-analysis on clinical and microbiological outcomes - PubMed
5 hours ago
- #Peri-implant Diseases
- #Meta-analysis
- #Systemic Antibiotics
- Systemic antibiotics (SA) do not provide significant clinical or microbiological benefits in treating peri-implant mucositis (PM).
- For peri-implantitis (PI) treatment, adjunctive SA leads to significant reductions in bleeding on probing and probing pocket depth at 12 months, but no significant improvement in marginal bone level.
- Only metronidazole showed notable effects on reducing specific pathogens like P. gingivalis and T. forsythia in PI treatment up to 12 months.
- The evidence highlights limited benefits of SA in PI, with heterogeneity in studies calling for more high-quality, long-term research.