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Efficacy of topical anesthetic cream, cold angiocath, and their combination on pain and fear during pediatric oncology venipuncture: A double-blind randomized controlled trial - PubMed

3 days ago
  • #Pediatric Oncology
  • #Pain Management
  • #Venipuncture
  • Study evaluates efficacy of topical anesthetic cream, cold angiocath, and their combination in reducing pain and fear during venipuncture in pediatric oncology patients.
  • 87 children aged 2-6 years undergoing outpatient chemotherapy were randomized into four groups: control, cold angiocath, Xylap cream, or combination.
  • Pain and fear were measured using the FLACC scale and Children's Fear Scale (CFS) at baseline and during three intervention sessions.
  • Combination therapy showed the greatest reduction in pain (-4.40) and fear (-1.39) compared to control (p < 0.001).
  • Xylap cream alone significantly reduced pain (-3.52) and fear (-0.96), while cold angiocath had smaller but significant effects (-1.62 for pain, -0.87 for fear).
  • Conclusion: Combination of topical anesthetic and cold angiocath is most effective for reducing venipuncture pain and fear in pediatric oncology patients.