Longitudinal and cross-sectional associations of myocardial stress markers with kidney function and chronic kidney disease in the BiomarCaRE project - PubMed
3 hours ago
- #Biomarkers
- #Cardiovascular Disease
- #Chronic Kidney Disease
- The study explores associations between myocardial stress markers (MR-proADM, MR-proANP, NT-proBNP) and kidney function/chronic kidney disease (CKD).
- Cross-sectional analysis of 61,830 participants showed higher marker levels linked to lower eGFR and higher CKD prevalence.
- Longitudinal analysis (NT-proBNP only) in 4,205 individuals revealed faster eGFR decline and higher CKD incidence with elevated baseline levels.
- Associations were stronger in participants with cardiovascular disease (CVD) and diabetes.
- Findings suggest these markers could serve as biomarkers for CKD.