Association of Autosomal Dominant Polycystic Kidney Disease With Incident Aortic Dissection or Aneurysm - PubMed
3 hours ago
- #Epidemiology
- #ADPKD
- #Aortic Dissection
- ADPKD is associated with an increased risk of aortic dissection (AD) or aortic aneurysm (AA).
- Study involved 2,568,283 individuals in Japan, with 1,102 diagnosed with ADPKD.
- Individuals with ADPKD had a significantly higher risk of AD or AA (HR 1.76).
- Risk was higher for AD (HR 2.53) compared to AA (HR 1.56).
- Association was stronger in individuals with BMI ≥ 25 kg/m².
- Limitations include potential residual confounding and lack of genetic mutation data.