Association between the estimated glucose disposal rate and new-onset chronic obstructive pulmonary disease in United States adults - PubMed
10 hours ago
- #COPD risk
- #public health
- #insulin resistance
- Study investigates the link between estimated glucose disposal rate (eGDR) and new-onset chronic obstructive pulmonary disease (COPD) in U.S. adults.
- Higher eGDR, indicating better insulin sensitivity, is associated with lower odds of COPD, with the relationship showing a non-linear pattern.
- An interaction with hypertension is noted: the inverse association is significant in individuals without hypertension but not in those with hypertension.
- eGDR demonstrates strong discriminatory power for COPD (AUC 0.82) and outperforms HOMA-IR in unadjusted models, with an optimal threshold of ~8.2 mg/kg/min.