Case Report: Infant with vaccine-associated paralytic poliomyelitis unveils global disparities in care for inborn errors of immunity - PubMed
3 hours ago
- #Healthcare Disparity
- #SCID
- #VAPP
- Case report of an Indonesian infant with severe combined immunodeficiency (SCID) and Omenn syndrome.
- Infant developed vaccine-associated paralytic poliomyelitis (VAPP) after receiving oral polio vaccine (OPV).
- Diagnosis delayed due to limited diagnostic capabilities in resource-limited settings.
- Highlights the need for improved diagnostic tools and transition from OPV to inactivated polio vaccine (IPV).
- Emphasizes the importance of newborn screening (NBS) for SCID in lower to middle income countries.
- Child passed away at 8 months due to febrile illness; family opted for palliative care over HSCT.