Association Between Inflammatory Cytokines and Systemic Inflammation Indices in Patients With Psoriasis: A Cross-Sectional Study - PubMed
5 days ago
- #cytokines
- #inflammation
- #psoriasis
- Study investigates the association between CBC-derived systemic inflammation indices and serum cytokines in psoriasis patients.
- 28 psoriasis patients and 23 healthy controls were included; serum cytokines and CBC-derived indices were measured.
- Psoriasis patients had higher levels of all cytokines and elevated SIRI compared to controls.
- TGF-β showed a global association with inflammation indices, but results did not remain significant after multiple testing corrections.
- SIRI and PIV showed the most consistent co-variation with cytokines, though associations were modest.
- Findings suggest the need for further validation in larger cohorts to assess CBC-derived indices as markers of inflammatory activity in psoriasis.