Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention - PubMed
3 days ago
- #Herpes Zoster
- #Varicella Zoster Virus
- #Clinical Management
- Varicella zoster virus (VZV) causes herpes zoster (HZ) upon reactivation, posing a clinical challenge in aging populations.
- HZ incidence increases with age and immunocompromised states, leading to complications like postherpetic neuralgia and systemic involvement.
- The disease involves viral reactivation, host immune surveillance, and virus-induced neuronal injury.
- Current interventions focus on individual disease stages, lacking comprehensive clinical strategies.
- Review covers VZV epidemiology, structure, life cycle, clinical manifestations, and molecular pathogenesis.
- Emphasis on latency, reactivation, immune evasion, diagnostic technologies, and therapeutic strategies.
- Highlights challenges in prevention and treatment, aiming for more effective interventions.