Effectiveness of non-pharmacological interventions for fatigue in long term conditions: systematic review and network meta-analysis - PubMed
5 hours ago
- #non-pharmacological interventions
- #systematic review
- #fatigue
- Systematic review and network meta-analysis assessed non-pharmacological interventions for fatigue in adults with long-term medical conditions.
- 88 randomized controlled trials involving 6636 participants were analyzed, with multiple sclerosis being the most common condition studied.
- Cognitive Behavioral Therapy (CBT) significantly reduced fatigue at the end of treatment and in long-term follow-up.
- Promotion of physical activity significantly reduced fatigue at all time points: end of treatment, short-term, and long-term follow-up.
- Self-management focusing on energy conservation showed benefits only in the long-term follow-up.
- The evidence strength was moderate to low, with effects appearing similar across different conditions.