The carcinogenicity of e-cigarettes: a qualitative risk assessment - PubMed
3 hours ago
- #public health
- #e-cigarettes
- #carcinogenicity
- Review summarizes qualitative carcinogenic risk assessment of nicotine-based e-cigarettes, focusing on evidence from 2017 onward.
- Evidence includes human studies showing DNA damage from carcinogens like nitrosamines and volatile compounds, plus oxidative stress and inflammation.
- Rodent bioassays indicate e-cigarette aerosol exposure can cause lung adenocarcinomas in mice.
- Mechanistic data suggest carcinogenicity involves a complex mixture with genotoxic and other processes.
- Conclusions have evolved from needing more evidence to expressing concern; e-cigarettes are likely carcinogenic, potentially contributing to oral and lung cancer.