The Safety Standards for Liver Percutaneous Thermal Ablation: A Meta-Analysis of Adverse Events over 15 Years - PubMed
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- #meta-analysis
- Percutaneous thermal ablation (PTA) is a curative therapy for small malignant liver neoplasms.
- The study aimed to update benchmarks for procedure-related mortality and major adverse events (AEs) after PTA.
- A meta-analysis of 49 studies (4149 patients, 4636 ablations) was conducted from 2007 to 2022.
- The pooled proportion of significant AEs was 3.0%, with a 90-day procedure-related mortality rate of 0.01%.
- No significant difference in AE rates was found between radiofrequency and microwave ablation or between hepatocellular carcinoma and metastatic tumors.
- PTA is associated with near-zero 90-day mortality and a 3% major complication rate.