Sperm storage causes sperm senescence in human and non-human animals - PubMed
3 hours ago
- #sperm senescence
- #reproductive biology
- #fertility
- Sperm storage in males and females can lead to post-meiotic sperm senescence (PMSS), causing deterioration.
- Meta-analysis shows in men, storage via sexual abstinence increases oxidative stress and DNA damage, reducing sperm viability and motility.
- In non-human animals, sperm storage in either sex reduces sperm performance, affecting fertilization success and embryo quality.
- Sampling methods in men and storage duration in animals influence observed outcomes of sperm deterioration.
- Findings have implications for fertility clinics, sperm selection, captive breeding, and understanding evolved adaptations to mitigate sperm deterioration.
- Results suggest optimizing the timing of ejaculate collection and storage can improve outcomes.